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Alumni

PDF of MSU PharmTox Alumni Listing

 

Ramya Kalyana Kumar, Ph.D.
Ramya Kalyana Kumar, Ph.D.

2020

Thesis Title: Sex-Differences In The Immune Axis Of Perivascular Adipose Tissues: In Health And Adiposity-Induced Hypertension

Advisor: Dr. Stephanie Watts

 

Jeremy Gingrich, Ph.D.
Jeremy Gingrich, Ph.D.

2020

Thesis Title: The Effects Of Endocrine Disrupting Chemicals On Placental Development And Function 

Advisor: Dr. Veiga-Lopez 

 

Robert Freeborn, Ph.D.
Robert Freeborn, Ph.D.

2020

Thesis Title: The Role Of NRF2 Activation On The Murine T Cell Response To Influenza Infection

Advisor: Dr. Cheryl Rockwell

 

Kevin Baker, Ph.D.
Kevin Baker, Ph.D.

2020

Thesis Title: Mechanisms Regulating Tissue Factor:Factor VIIA-Dependent Coagulation In Liver Disease

Advisor: Dr. James Luyendyk

 

David Ferland, Ph.D.
David Ferland, Ph.D.

2020

Thesis Title: Chemerin As A Link Between Hypertension And Obesity  

Advisor: Dr. Stephanie Watts

 

Vanessa Benham, Ph.D.
Vanessa Benham, Ph.D.

2020

Thesis Title: Investigating The Mechanism Of Obesity-Associated Estrogen Receptor-Negative Breast Cancer To Identify Novel Agents For Chemoprevention 

Advisor: Dr. Jamie Bernard 

 

Di Zhang, Ph.D.
Di Zhang, Ph.D.

2020

Thesis Title: Applying Synthetic Chemistry And Nanoparticle Delivery To Enhance Drug Efficacy And Reduce Toxicity For Cancer Prevention And Treatment.

Advisor: Dr. Karen Liby

 

Bridget M. Seitz, Ph.D.
Bridget M. Seitz, Ph.D.

2019

Thesis Title: The Systemic And Regional Hemodynamic Changes Responsible For 5-HT7 Receptor Mediated Hypotension

Advisor: Dr. Gregory Fink

 

Evert Njomen, Ph.D.
Evert Njomen, Ph.D.

2019

Dual Ph.D. Major (Chemistry, Pharmacology & Toxicology)

Thesis Title: The Discovery And Characterization Of Small Molecule 20S Proteasome Activators: Implications In Proteostasis Disorders

Advisor: Dr. Jetze Tepe 

 

Janice Diaz-Otero, Ph.D.
Janice Diaz-Otero, Ph.D.

2019

Thesis Title: Endothelial Mineralocorticoid Receptors In Cerebrovascular And Cognitive Function In Angiotensin Il-Hypertension

Advisor: Dr. Anne Dorrance

 

Huijie "Jade" Feng, Ph.D.
Huijie "Jade" Feng, Ph.D.

2019

Thesis Title: Mechanisms Of GNAO1-Associated Neurological Disorders

Advisor: Dr. Richard Neubig

 

Kibrom Alula, Ph.D.
Kibrom Alula, Ph.D.

2019

Thesis Title: Effect Of High-Fat Diet On Sympathetic Neurotransmission In Mesenteric Vasculature In Dahl Salt-Sensitive Hypertension

Advisor: Dr. James Galligan 

 

Alberto Perez-Medina, Ph.D.
Alberto Perez-Medina, Ph.D.

2019

Thesis Title: Optogenetic Analysis Of Excitatory And Inhibitory Neurotransmission In The Enteric Nervous System

Advisor: Dr. James Galligan 

 

Vincent Shaw, Ph.D.
Vincent Shaw, Ph.D.

2019

Thesis Title: Understanding Specificity Of Small Molecule Inhibitors Of Regulators Of G-Protein Signaling (RGS) Proteins

Advisor: Dr. Richard Neubig

 

Elizabeth Williams, Ph.D.
Elizabeth Williams, Ph.D.

2019

Thesis Title: Androgen-dependent Excitability Of Mouse Ventral Hippocampal Afferents To Nucleus Accumbens Underlies Sex-Specific Susceptibility To Stress

Advisor: Dr. A.J. Robison 

 

Alexandra Turley, Ph.D.
Alexandra Turley, Ph.D.

2018

Thesis Title: The Role of NRF2 In The Activation Of Primary CD4 Cells From Mice And Humans

Advisor: Dr. Cheryl Rockwell 

 

Hoa Phan, Ph.D.
Hoa Phan, Ph.D.

2018

Thesis Title: Effects Of Human RGS2 Protein Mutations In Cardiovascular Disease

Advisor: Dr. Richard Neubig

 

Joseph Henriquez, Ph.D.
Joseph Henriquez, Ph.D.

2018

Thesis Title: Δ9- Tetrahydrocannabinol-Mediated Suppression Of The Interferon- α (IFNα) Response By Plasmacytoid Dendritic Cells And IFNα-Mediated Activation of T Cells In Healthy And Human Immunodeficiency Virus (HIV) Infected Human Subjects

Advisor: Dr. Norbert Kaminski 

 

Juliette Brown, Ph.D.
Juliette Brown, Ph.D.

2017

Thesis Title: The Role Of Lateral Hypothalamic Neurotensin Neurons In Adaptive Energy Balance

Advisor: Dr. Gina Leinninger 

 

Nadine El-Ayache, Ph.D.
Nadine El-Ayache, Ph.D.

2017

Thesis Title: Serotonergic Signaling At 5-HT 3 Receptors In Serotonin  Transporter (SERT) Knockout (KO) Rat, A Sex Specific Animal Model Of Visceral Hypersensitivity

Advisor: Dr. James Galligan 

 

Sophia Kaska, Ph.D.
Sophia Kaska, Ph.D.

2017

Thesis Title: Investigating the Role of Ventral Tegmental Area TORC2 in Stress and Stress-Induced Changes in Opiate Reward

Advisor: Dr. Michelle Mazei-Robison

 

Theresa Lansdell, Ph.D.
Theresa Lansdell, Ph.D.

2017

Thesis Title: The Role of Parkin in Maintaining Proteasome Activity Following Acute Neurotoxic Insult

Advisors: Dr. John Goudreau & Dr. Keith Lookingland 

 

Brittany Winner, Ph.D.
Brittany Winner, Ph.D.

2017

Thesis Title: UCH-L1 as a Susceptibility Factor for Nigrostriatal and Mesolimbic Dopamine Neurons After Neurotoxicant Exposure and Aging

Advisors: Dr. John Goudreau & Dr. Keith Lookingland 

 

Isola Brown, Ph.D.
Isola Brown, Ph.D.

2017

Thesis Title: Enteric Glial Cell Regulation of Oxidative Stress and Immune Homeostasis During Gastrointestinal Inflammation

Advisor: Dr. Brian Gulbransen 

Nadia Ayala-Lopez, Ph.D.
Nadia Ayala-Lopez, Ph.D.

2016

Thesis Title:  A New Role for PVAT: Regulation of Blood Vessel Function Through the Control of Norepinephrine

Advisor:  Dr. Stephanie Watts

Nusrat Matin, Ph.D.
Nusrat Matin, Ph.D.

2016

Thesis Title:  The effects of soluble epoxide hydrolase inhibition in a hypertensive model of cognitive impairment

Advisor:  Dr. Anne Dorrance

Natalia Kovalova, Ph.D.
Natalia Kovalova, Ph.D.

2016

Thesis Title:  Role of Aryl Hydrocarbon Receptor Polymorphisms on TCDD-mediated CYP1B1 Induction and IgM Suppression by Human B cells

Advisor:  Dr. Norb Kaminski

Nikita Joshi, Ph.D.
Nikita Joshi, Ph.D.

2016

Thesis Title: Hepatoprotective functions of the hemostatic system in experimental xenobiotic-induced biliary injury

Advisor:  Dr. Jim Luyendyk 

Ashley Maiuri, Ph.D.
Ashley Maiuri, Ph.D.

2015

Thesis Title: Drug-Cytokine Cytotoxic Interaction: Relationship to Idiosyncractic, Drug-Induced Liver Injury

Advisor:  Dr. Bob Roth

Kate O'Brien, Ph.D.
Kate O'Brien, Ph.D.

2014

Thesis Title: Elucidation of the Mechanisms of Interaction Between Bile Acids and the Interleukin-23/Interleukin-17 Axis During Cholestasis

Advisor: Dr. Bryan Copple

Jeremiah Phelps, Ph.D.
Jeremiah Phelps, Ph.D.

2014

Thesis Title: Mechanisms by which Remanl Denervation Chronically Lowers Blood Pressure in the Spontaneously Hypertensive Rat

Advisor: Dr. Gregory Fink

Ninitha Asirvathamjeyaraj, Ph.D.
Ninitha Asirvathamjeyaraj, Ph.D.

2013

Thesis Title: Role of Central Eicosanoids in the Development of Angiotensin II-Salt Hypertension in the Rat

Advisor: Dr. Gregory Fink

Kevin Beggs, Ph.D.
Kevin Beggs, Ph.D.

2013

Thesis Title: Mechansims of Hepatocellular Apoptosis by Trovafloxacin-tumor Necrosis Factor-Alpha Interaction: An In Vitro Model of Idiosyncractic Drug-Induced Liver Injury

Advisor: Dr. Bob Roth

Sara Ciotti, Ph.D.
Sara Ciotti, Ph.D.

2013

Thesis Title: Disruption of Cellular Calcium Homeostasis and Mitochondrial Function Following Chronic Methylmercury Treatment

Advisor: Dr. Bill Atchison

Aaron Fullerton, Ph.D.
Aaron Fullerton, Ph.D.

2013

Thesis Title: 2,3,7,8-TCDD Alters the Development and Severity of Hepatotoxicity in a Mouse Model of Immune-Mediated Liver Injury Induced by Concanavalin A

Advisor: Dr. Patti Ganey

Thitirat Ngaotepprutaram, Ph.D.
Thitirat Ngaotepprutaram, Ph.D.

2013

Thesis Title: Suppression of the T-cell dependent Humoral Immune Response by Δ9-Tetrahydrocannabinol Involves Impairment of CD40-CD40 Ligand Interaction

Advisor: Dr. Norb Kaminski

Paulo Pires, Ph.D.
Paulo Pires, Ph.D.

2013

Thesis Title: The Role of Inflammatory Mediators in Hypertensive Remodeling of Cerebral Arteries: Focus on Perivascular Macrophages, Matrix Metalloproteinases and Tumor Necrosis Factor-α

Advisor: Dr. Anne Dorrance

Kyle Poulsen, Ph.D.
Kyle Poulsen, Ph.D.

2013

Thesis Title: Trovafloxacin Potentiates Lipopolysaccharide-induced Tumor Necrosis Factor-alpha in a Macrophage Cell-Line: Mechanistic Insights into Idiosyncratic Liability

Advisor:  Dr. Bob Roth

Joseph Prinsen, Ph.D.
Joseph Prinsen, Ph.D.

2013

Thesis Title: Insights into the Effect of Tachycardia Irregularity on
Ventricular Repolarization Dynamics

Advisor: Dr. N. Bari Olivier

Sutheera Sangsiri, Ph.D.
Sutheera Sangsiri, Ph.D.

2013

Thesis Title: Impaired Function of PreJunctional Adenosine Receptors on Perivascular Sympathetic Nerves in Salt-Sensitive Hypertension

Advisor: Dr. Jim Galligan

Loc Vinh Thang, Ph.D.
Loc Vinh Thang, Ph.D.

2013

Thesis Title: Macrophage (MΦ)-derived Superoxide Disrupts Sympathetic Nerve Function In Deoxycorticosterone Acetate (DOCA)-Salt Hypertensive Rats

Advisor: Dr. Jim Galligan

Priya Balasubramanian, Ph.D.
Priya Balasubramanian, Ph.D.

2012

Thesis Title: Prenatal Stress Mediated Fetal Programming of Obesity in Diet-Induced Obese and Dietary Resistant Rats.

Advisor: Dr. Sheba MohanKumar

Nathan Tykocki, Ph.D.
Nathan Tykocki, Ph.D.

2012

Thesis Title: Endothelin-1-Induced Calcium Signaling in Artieries and Veins

Advisor: Dr. Stephanie Watts

Robert Davis, Ph.D.
Robert Davis, Ph.D.

2011

Thesis Title: Mechanism of 5-Hydroxytryptamine-Induced Hypotension

Advisor: Dr. Stephanie Watts

Priyadarshini Raman, Ph.D.
Priyadarshini Raman, Ph.D.

2011

Thesis Title: Suppression of Interleukin-2 Secretion by 15 Deoxy-Prostaglandin J2-Glycerol, a Putative Cyclooxygenase-2 Metabolite of 2-Arachidonyl Glycerol, Involves the Activation of Peroxisome Proliferator Activated Receptor Gamma

Advisor: Dr. Norb Kaminski

Erica Sparkenbaugh, Ph.D.
Erica Sparkenbaugh, Ph.D.

2011

Thesis Title:  The Role of Neutrophil Elastase, Hypoxia and HIF-1α in Hepatocellular Injury

Advisor: Dr. Bob Roth

Sachin Kandlikar, Ph.D.
Sachin Kandlikar, Ph.D.

2010

Thesis Title: Sympathetic Nervous System in the Development of Mild DOCA-Salt Hypertension

Advisor: Dr. Greg Fink

Haitian Lu, Ph.D.
Haitian Lu, Ph.D.

2010

Thesis Title: Mechanism for 2,3,7,8-Tetrachlorodibenzo-p-Dioxin-Mediated Effects on CD40 Ligand-Induced Activation and Effector Function of Primary Human and Mouse B Cells

Advisor: Dr. Norb Kaminski

Erika Boerman Westcott, Ph.D.
Erika Boerman Westcott, Ph.D.

2010

Thesis Title: Regulation of Subsarcolemmal CA2+ Oscillations and Myogenic Tone in the Microcirculation

Advisor: Dr. William Jackson

Colin North, Ph.D.
Colin North, Ph.D.

2009

Thesis Title: In Vivo and In Vitro Mechanisms for Disruption of the Toll-Like Receptor Activated Primary Immunoglobulin M Response by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)

Advisor: Dr. Norb Kaminski

Alexandra Hlavacova, Ph.D.
Alexandra Hlavacova, Ph.D.

2008

Thesis Title: Enhanced Adrenergic Sensitivity of Mesenteric Veins Compared to Arteries and its Relation to Calcium Utilization and Handling

Advisor: Dr. James Galligan

Andrew King, Ph.D.
Andrew King, Ph.D.

2008

Thesis Title: Neurogenic Mechanisms of Salt-Sensitive Hypertension

Advisor: Dr. Greg Fink

Wei Li, Ph.D.
Wei Li, Ph.D.

2008

Thesis Title: The Effects of Chronic Activation of Endothelin ETB Receptors on Blood Pressure, Venomotor Tone, Neurohumoral Activity, and Oxidative Stress

Advisor: Dr. Greg Fink

Dina Schneider, Ph.D.
Dina Schneider, Ph.D.

2008

Thesis Title: The Role of Pax5, Blimp-1 and AP-1 in the Suppression of B Cell Differentiation of TCDD

Advisor: Dr. Norb Kaminski

Patrick Shaw, Ph.D.
Patrick Shaw, Ph.D.

2008

Thesis Title: Inflammation and Idiosyncratic Drug Reactions: Inflammatory Mechanisms and Interactions in a Murine Model of Trovafloxacin Hepatotoxicity

Advisor:  Dr. Bob Roth

John Buchweitz, Ph.D.
John Buchweitz, Ph.D.

2007

Thesis Title: Characterization of Delta-9-Tertrahydrocannabinol-Mediated Alterations in Leukocyte and Airway Epithelial Cell Responses to a Primary Challenge with Influenza A/PR/8/34 in C57BL/6 Wild Type and CB1/CB2 Receptor-Null Mice

Advisor: Dr. Norb Kaminski

Ammie Bachman, Ph.D.
Ammie Bachman, Ph.D.

2006

Thesis Title: Altered Pattern of Methylation in Gene-specific and GC-rich Regions of DNA Underlie Tumorigenesis

Advisor: Dr. Jay Goodman

Steven Bezdecny, Ph.D.
Steven Bezdecny, Ph.D.

2006

Thesis Title: Signal Transduction Pathways Involved in the Upregulation of Cyclooxygenase-2 by 2,2',4,4',-Tetrachlorobiphenyl

Advisor: Dr. Patti Ganey

Wei Ni, Ph.D.
Wei Ni, Ph.D.

2006

Thesis Title: The Presence of A Local Serotonergic System in Peripheral Arteries

Advisor: Dr. Stephanie Watts

Keshari Thakali
Keshari Thakali

2006

Thesis Title: Endothelin A (ETA) and ETB Receptor Interaction in Arteries and Veins

Advisor:  Dr. Stephanie Watts

Lyle Burgoon, Ph.D.
Lyle Burgoon, Ph.D.

2005

Thesis Title: Design, Management, and Quality Control of Toxicogenomics Experiments

Advisor: Dr. Jim Galligan

Alex Perez-Rivera, Ph.D.
Alex Perez-Rivera, Ph.D.

2005

Thesis Title: Alpha-1 Adrenergic Receptor Function and Protein Expression in Arteries and Veins from Normal and Hypertensive Mice

Advisor: Dr. Jim Galligan

Gautham Rao, Ph.D.
Gautham Rao, Ph.D.

2005

Thesis Title: Involvement of TRPC1 in the Cannabinoid-Mediated Elevation in Intracellular Calcium in T Cells

Advisor: Dr. Norb Kaminski

Cheryl Rockwell, Ph.D.
Cheryl Rockwell, Ph.D.

2005

Thesis Title: Inhibition of Interleukin-2 Secretion by 2-Arachidonyl Glycerol and Anandamide Occurs through Perixsome Proliferator Activated Receptor Gamma Independently of the Cannabinoid Receptors

Advisor: Dr. Norb Kaminski

Hong Wang, Ph.D.
Hong Wang, Ph.D.

2005

Thesis Title: Neurohumoral Control of Splanchnic Circulationin DOCA-Salt Hypertensive Rats

Advisor: Dr. Greg Fink

Diana Ye, Ph.D.
Diana Ye, Ph.D.

2005

Thesis Title: Low-potency Poly (ADP-Ribose) Polymerase Inhibitors (Ip-PARPi) Induce Insulin Gene Expression through the Upregulation of MafA in INS-1 Pancreatic-Cells

Advisor: Dr. Karl Olson