PHM 450 - Introduction to Chemical Toxicology

Description

This online course provides an introduction to mammalian toxicology. The course includes an overview of the general principles of toxicology, toxicokinetics, and mechanisms of
toxicity in major organ systems. The course also includes discussion of selected toxic agents. 

Individuals not affiliated with the University may enroll in this course as a Lifelong Education Student. Introduction to Chemical Toxicology is open to anyone with a prerequisite knowledge of biology and chemistry, and an interest in learning more
about toxicology.

Topics

• Cellular and molecular mechanisms of toxicity
• Toxicokinetics
• Mutagenesis and carcinogenesis
• Hepatic and renal toxicology
• Neurotoxicology and immunotoxicology
• Cardiovascular and respiratory toxicology
• Teratogenesis
• Toxicology within the drug development process
• Pharmaceuticals as toxicants
• Environmental toxicology
• Chemical risk assessment

Pre-requisites

BS 161, and BS 162, and CEM 251

Textbooks

Required for online sections of this course:

ESSENTIALS OF TOXICOLOGY
Paperback: 544 pages

• Publisher: McGraw-Hill Education / Medical 
  3 edition, 2015
• ISBN-10: 0071847081
• ISBN-13: 978-0071847087

 

Required for on-campus (Spring semester) section of this course:

PRINCIPLES OF BIOCHEMICAL TOXICOLOGY

Hardcover: 464 pages
Publisher: CRC Press
4th edition, 2008
Language: English
ISBN-10: 0849373026
ISBN-13: 978-0849373022

 

Instructors

• Dr. Tobi Limke Received her PhD in Pharmacology & Toxicology-Environmental Toxicology from Michigan State University. She also holds an MBA from the University of Maryland. A postdoctoral fellow at the National Institute on Aging at the National Institutes of Health in Baltimore, MD, Dr. Limke has experience working with classic pharmaceutical and biotechnology companies in both scientific and business roles. Currently, she works as a freelance technical marketing consultant for the biopharmaceutical industry.
• Dr. Belinda Hawkins holds a PhD in Pharmacology & Toxicology-Environmental Toxicology from Michigan State University. She works for the US-EPA in Cincinnati, OH. She is currently Chief of the Chemical Risk Assessment Branch within EPA’s National Center forEnvironmental Assessment.