Description

Core principles of pharmacology and toxicology including pharmacokinetics, toxicokinetics (drug/toxicant absorption, distribution, metabolism, elimination, modeling), pharmacodynamics (drug-receptor and drug-enzyme interactions), and drug discovery.

Topics

• Pharmacokinetics/toxicokinetics
• Pharmacodynamics/toxicodynamics
• Drug-receptor interactions
• Chemical enzyme interactions
• Drug tolerance and dependence
• Drug discovery and design

Recommended Textbooks

Goodman & Gilman’s
The Pharmacological Basis of Therapeutics
12th edition, 2010

Pharmacology Principles and Practice 2009
M. Hacker et al

Requirements

Open to doctoral students or approval of department. Not open to students who have taken PHM 819.

Instructor(s)

Dr. Keith Lookingland is an Associate Professor in the Dept of Pharmacology & Toxicology and a member of the CIT, Genetics, and Neuroscience Programs. Research involves development of neuroprotective strategies for treating dopamine neurodegenerative disorders such as Parkinson’s Disease and Restless Leg Syndrome.