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PHM 817 - Neurotoxicology*

Description

Biochemical, molecular, physiological mechanisms and assessment of neurotoxicity. Factors predisposing the nervous system to selective toxicants. Pathophysiology and models of toxicant-induced neurodegenerative diseases.

Topics

  • General principles of toxicology
  • Review of toxicokinetics
  • Overview of normal structure and function of the nervous system
  • Aspects of normal cellular neurophysiology
  • Mechanisms of neurotoxicity
  • Glial-neuronal interactions and neuro- inflammation
  • Neurotransmission-associated neurotoxicity
  • Models of neurodegenerative disease
  • Neurotoxicity assessment
  • Pharmacological neuroprotective strategies

Pre-requisites

PHM 819 and PHM 450 or equivalent

pharmacology & toxicology courses;

undergraduate biochemistry and cell biology

Recommended Textbooks

book cover

Casarett & Doull's Toxicology: The Basic Science of Poisons

8th Edition
McGraw-Hill Professional
Publisher: McGraw-Hill Education / Medical; 8 edition (June 19, 2013) Language: English
ISBN-10: 0071769234    
ISBN-13: 978-0071769235

INSTRUCTOR

Dr. Colleen Hegg

Semesters

Online Spring

Credits

2

Programs

  • MS/Pharmacology &Toxicology
  • MS/Integrative Pharmacology
  • Grad Cert/SafetyPhm

Type

Science

Sections available

  • 730 MSU program Students
  • 731 Lifelong In-State
  • 732 Lifelong Out-State