PHM 841 - Cellular And Molecular Toxicology
Mechanistic concepts and techniques of toxicology at the cellular and molecular levels. Various molecular events and cellular modifications that result from and/or are associated with chemically/environmentally induced toxicity and disease.
- Molecular techniques in toxicology
- Cellular techniques in toxicology
- Cytochrome P450
- Phase I-Metabolism of toxicants
- Phase II-Conjugation of toxicants
- Xenobiotic transporters
- Mechanisms of cell death
- Mitochondrial dysfunction
- Oxidative stress
- Reactive oxygen species
- Toxicity of metals
- DNA damage and mutagenesis/DNA repair
PHM 450 or equivalent introductory toxicology course required.
Molecular and Biochemical Toxicology
Dr. Jane Maddox is the Co-Director of the online MS program in Pharmacology & Toxicology. She received her DVM from Michigan State University. Following a few years of private practice, she earned her PhD in Pathobiology from Pennsylvania State University and held a postdoctoral position at Harvard. Her research interests include inflammation and mechanisms of druginduced liver injury.
- Grad Cert/ SafetyPhm
- 730 MSU program Students
- 731 Lifelong In-State
- 732 Lifelong Out-State