Fields of Interest: The Dorrance Lab is committed to understanding the pathogenesis of hypertension- and obesity-related cerebrovascular disease with the goal of identifying novel treatments for stroke and dementia.
Fields of Interest: My research concerns the causes of systemic arterial hypertension, a major world-wide risk factor for cardiovascular disease morbidity and mortality.
Fields of Interest: "Purinergic neurotransmission in the intestine", "Neural control of arteries and veins in hypertension", "SERT KO rats are a model of sex specific
Fields of Interest: Our research program is focused on neurotransmitter regulation and function in the paraventricular nucleus of the hypothalamus in normotensive and hypertensive animals.
Fields of Interest: Examination of how arterioles in the microcirculation sense their environment; the role of smooth muscle and endothelial cell ion channels in the regulation of calcium signaling; vascular cell signaling related to vasodilation and vasoconstriction.
Fields of Interest: G protein-coupled receptor (GPCR) signaling and intracellular modulators of that signaling. GPCRs are the targets of over 30% of current drugs and we are discovering novel ways to control their function.
Fields of Interest: My research works focus on the autonomic nervous system, molecular signaling and receptor/ion channel interaction in the vasculature, and how these factors regulate smooth muscle and vascular tone in health and human diseases.
