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Fields of Interest: G protein-coupled receptor (GPCR) signaling and intracellular modulators of that signaling. GPCRs are the targets of over 30% of current drugs and we are discovering novel ways to control their function.
Fields of Interest: The Dorrance Lab is committed to understanding the pathogenesis of hypertension- and obesity-related cerebrovascular disease with the goal of identifying novel treatments for stroke and dementia.
Fields of Interest: My research concerns the causes of systemic arterial hypertension, a major world-wide risk factor for cardiovascular disease morbidity and mortality.
Fields of Interest: "Purinergic neurotransmission in the intestine", "Neural control of arteries and veins in hypertension", "SERT KO rats are a model of sex specific
Fields of Interest: My research works focus on the autonomic nervous system, molecular signaling and receptor/ion channel interaction in the vasculature, and how these factors regulate smooth muscle and vascular tone in health and human diseases.
Fields of Interest: Our research program is focused on neurotransmitter regulation and function in the paraventricular nucleus of the hypothalamus in normotensive and hypertensive animals.
Fields of Interest: Examination of how arterioles in the microcirculation sense their environment; the role of smooth muscle and endothelial cell ion channels in the regulation of calcium signaling; vascular cell signaling related to vasodilation and vasoconstriction.
Adam Lauver, Ph.D.
Richard Neubig, M.D., Ph.D.
Anne Dorrance, Ph.D.
Gregory Fink, Ph.D.
James Galligan, Ph.D.
Stephanie Watts, Ph.D.
Hui Xu, M.D., Ph.D.
JR Haywood, Ph.D.
William F. Jackson, Ph.D.