Kyle Poulsen, PhD
Assistant Professor
Lab Postdocs
Colleges
Funding
- HEPATOCYTE-DERIVED MIF: A KEY CONTRIBUTOR TO ALCOHOLIC LIVER DISEASE, National Institute on Alcohol Abuse and Alcoholism (2018-08-10—2024-08-31)
- Receptor Cd74 integrates meta-inflammation in alcohol-associated liver disease, National Institute on Alcohol Abuse and Alcoholism (2024-09-01—2029-07-31)
- Role of macrophage migration inhibitory factor in an acutely severe model of alcoholic hepatitis, National Institute On Alcohol Abuse and Alcoholism (2016-05-16—2018-08-09)
- Hepatocyte-derived MIF: a key contributor to Alcoholic Liver Disease, National Institute On Alcohol Abuse and Alcoholism (2018-08-10—2020-07-31)
Works
- Updates on the Immune Cell Basis of Hepatic Ischemia-Reperfusion Injury. Molecules and Cells (2023)
- Hepatic recruitment of eosinophils and their protective function during acute liver injury. Journal of Hepatology (2022)
- Radiofrequency ablation remodels the tumor microenvironment and promotes systemic immunomodulation in pancreatic cancer. (2022-01-10)
- Role of MIF in coordinated expression of hepatic chemokines in patients with alcohol-associated hepatitis. JCI Insight (2021-05-04)
- Inhibition of IRAK4 kinase activity improves ethanol-induced liver injury in mice. Journal of Hepatology (2020)
- MLKL-dependent signaling regulates autophagic flux in a murine model of non-alcoholic fatty liver disease. Journal of Hepatology (2020)
- Novel Role of Macrophage Migration Inhibitory Factor in Upstream Control of the Unfolded Protein Response After Ethanol Feeding in Mice. Alcoholism: Clinical and Experimental Research (2019)
- The non-transcriptional activity of IRF3 modulates hepatic immune cell populations in acute-on-chronic ethanol administration in mice. Journal of Hepatology (2019)
- Anaphylatoxin receptors C3aR and C5aR1 are important factors that influence the impact of ethanol on the adipose secretome. Frontiers in Immunology (2018)
- Complement factor d protects mice from ethanol-induced inflammation and liver injury. American Journal of Physiology - Gastrointestinal and Liver Physiology (2018)
- Hepatic Immune System: Adaptations to Alcohol. Handbook of Experimental Pharmacology (2018)
- Hepatocyte-derived macrophage migration inhibitory factor mediates alcohol-induced liver injury in mice and patients. Journal of Hepatology (2017)
- Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia telangiectasia and Rad3-related. Toxicology (2015)
- Trovafloxacin enhances lipopolysaccharide-stimulated production of tumor necrosis factor-α by macrophages: Role of the DNA damage responses. Journal of Pharmacology and Experimental Therapeutics (2014)
- Trovafloxacin potentiation of Lipopolysaccharide-Induced Tumor necrosis factor release from RAW 264.7 Cells requires extracellular signal-regulated kinase and c-Jun N-Terminal kinases. Journal of Pharmacology and Experimental Therapeutics (2014)
Employment
- Assistant Professor, Michigan State University (2025-01-01)
- Assistant Professor, Texas Medical Center (2020-09-01—2024-12-31)