Bin Chen , PhD

Biography

I am a tenured associate professor leading a multidisciplinary lab, with a mission to leverage advanced machine learning and emerging big data to discover new therapeutics. I am also the Founding PI of the Center for AI-Enabled Drug Discovery in the College of Human Medicine at MSU. My current research areas include machine learning method development, integrative bioinformatics, and EHR mining. I have training in informatics, chemistry, and biology, and working experience in big pharmaceutical companies and small startups. As a corresponding author, I have published in many high-profile journals such as Cell, Nature Protocols, Nature Reviews Gastroenterology & Hepatology, Nature Communications, Cell Systems, Genomics, Proteomics & Bioinformatics, and Briefings in Bioinformatics. As a PI/co-PI, I have received a K01 career training award, multiple R01-level NIH grants, industry-sponsored grants, and foundation grants, totaling over $7 million. I have served as a mentor/co-mentor for two K99 training grants and have mentored four trainees who have gone on to become PIs. In the next few years, I aim to pioneer transcriptomics-based drug discovery, develop foundational models to understand how individual cells respond to perturbations, and utilize massive real-world data to assess drug efficacy.