Jonathan Diedrich , PhD

Assistant Professor

Education

PhD, Cancer Biology, Wayne State University, 2012
B.S., Zoology, Michigan State University, 2008

Employment

Assistant Professor, Michigan State University, East Lansing, 2025 - Present
Assistant Professor - Fixed Term, Michigan State University, East Lansing, 2024 - 2024
Senior Research Associate, Michigan State University, East Lansing, 2021 - 2024
Postdoctoral Fellow, St. Jude Children's Research Hospital, Memphis, 2017 - 2020

Publications

Investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment Nature Communications (2024)

Epigenomic mapping reveals distinct B cell acute lymphoblastic leukemia chromatin architectures and regulators Cell Genomics (2023)

Non-Toxicological Role of Aryl Hydrocarbon Receptor in Obesity-Associated Multiple Myeloma Cell Growth and Survival Cancers (2023)

Adipocyte-derived kynurenine stimulates malignant transformation of mammary epithelial cells through the aryl hydrocarbon receptor Biochemical Pharmacology (2023)

Epigenomic mapping in B-cell acute lymphoblastic leukemia identifies transcriptional regulators and noncoding variants promoting distinct chromatin architectures (2023)

Functional investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment (2023)

Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia Leukemia (2022)

Epigenetic activation of the FLT3 gene by ZNF384 fusion confers a therapeutic susceptibility in acute lymphoblastic leukemia Nature Communications (2022)

Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia Blood Advances (2022)

Profiling chromatin accessibility in pediatric acute lymphoblastic leukemia identifies subtype-specific chromatin landscapes and gene regulatory networks Leukemia (2021)

Fundings

Bone Marrow Adipocytes Alter the Metabolic Phenotype of Metastatic Prostate Cancer

Bone Marrow Adipocytes Modulate Tumor Metabolism in Metastatic Prostate Cancer Cells

Identification of Cis-Regulatory Elements that Predict ALL Resistance

Implifications of AhR modulation by bone marrow adipocytes in multiple myeloma

In the News

Jonathan Diedrich

Post-doc Experience at St. Jude Proves Invaluable to Dr. Diedrich in His New Role as Assistant Professor

Learning from "experts" in the field of pharmacogenomics.has helped him chart his course at MSU, where his research concentrates on multiple myeloma progression and the development of drug resistance.