Edmund Ellsworth , PhD

Publications

Lipid-Based Self-Microemulsion of Niclosamide Achieved Enhanced Oral Delivery and Anti-Tumor Efficacy in Orthotopic Patient-Derived Xenograft of Hepatocellular Carcinoma in Mice. International journal of nanomedicine (2024)

The Novel RXR Agonist MSU-42011 Differentially Regulates Gene Expression in Mammary Tumors of MMTV-Neu Mice International Journal of Molecular Sciences (2023)

Anti-fibrillization effects of sulfonamide derivatives on α-synuclein and hyperphosphorylated tau isoform 1N4R Journal of Molecular Structure (2022)

Small Molecule 20S Proteasome Enhancer Regulates MYC Protein Stability and Exhibits Antitumor Activity in Multiple Myeloma Biomedicines (2022)

Machine Learning Analysis of Cocaine Addiction Informed by DAT, SERT, and NET-Based Interactome Networks Journal of Chemical Theory and Computation (2022)

Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane Biochemical Journal (2021)

The RXR Agonist MSU42011 Is Effective for the Treatment of Preclinical HER2+ Breast Cancer and Kras-Driven Lung Cancer Cancers (2021)

The novel rexinoid MSU-42011 is effective for the treatment of preclinical Kras-driven lung cancer Scientific Reports (2020)

Therapeutic potential of targeting mixed lineage kinases in cancer and inflammation Pharmacology & Therapeutics (2020)

Inhibiting Mycobacterium tuberculosis DosRST Signaling by Targeting Response Regulator DNA Binding and Sensor Kinase Heme ACS Chemical Biology (2020)