William Jackson , PhD
Biography
Dr. Jackson is Professor of Pharmacology and Toxicology at Michigan State University. Received his Ph.D. in Physiology from Michigan State University in 1979 and was a postdoctoral fellow in Dr. Brian Duling’s lab in the Department of physiology at the University of Virginia. He then moved to the Department of Physiology and Endocrinology at the Medical College of Georgia where is rose from the rank of Assistant Professor to Associate Professor. He then moved to the Department of Biological Sciences at Western Michigan University where he rose to the rank of Professor. In 1998 he was named a Distinguished Faculty Scholar WMU’s highest award for his research accomplishments. In 2005 he was recruited back to MSU to start an online Professional Science Masters program in Integrative Pharmacology and is the founding Director of this program. Dr. Jackson’s research focuses on identifying the ion channels expressed by both arteriolar smooth muscle and endothelial cells, how these ion channels function in the regulation of myogenic tone; the mechanisms underlying vasoconstriction and vasodilation; oxygen signaling in the microcirculation. and how aging and disease states such as hypertension and obesity impact the expression and function of ion channels in the microcirculation.
Education
M.S. Applied Mathematics, Mathematics, Michigan State University, 1978
Ph.D., Physiology, Michigan State University, 1976
M.S., Physiology, Michigan State University, 1974
B.S., Zoology, Michigan State University, 1970
Employment
Professor, Michigan State University, East Lansing, 2005 - Present
Professor, Western Michigan University, Kalamazoo, 1989 - 2005
Associate Professor, Augusta University Medical College of Georgia, Augusta, 1983 - 1989
Publications
Sometimes Smaller Is Better Circulation Research (2025)
High-fat feeding has sex-dependent effects on the structure and biomechanical properties of cerebral parenchymal arterioles and cognitive function American Journal of Physiology-Heart and Circulatory Physiology (2025)
Innervation of adipocytes is limited in mouse perivascular adipose tissue American Journal of Physiology-Heart and Circulatory Physiology (2024)
The conducted vasomotor response and the principles of electrical communication in resistance arteries Physiological Reviews (2024)
5‐HT7 receptors mediate dilation of rat cremaster muscle arterioles in vivo Microcirculation (2023)
Female mice are protected from impaired parenchymal arteriolar TRPV4 function and impaired cognition in hypertension American Journal of Physiology-Heart and Circulatory Physiology (2023)
Genetic ablation of smooth muscle KIR2.1 is inconsequential to the function of mouse cerebral arteries Journal of Cerebral Blood Flow & Metabolism (2022)
Poorly controlled hypertension is associated with increased coronary myogenic tone in patients undergoing cardiac surgery with cardiopulmonary bypass The Journal of Thoracic and Cardiovascular Surgery (2022)
The heat is on! TRPV1 channels and resistance artery myogenic tone The Journal of Physiology (2022)
Endothelial Ion Channels and Cell-Cell Communication in the Microcirculation Frontiers in Physiology (2022)