Maike Krenz , MD

Publications

TRPV4 increases cardiomyocyte calcium cycling and contractility yet contributes to damage in the aged heart following hypoosmotic stress Cardiovascular Research (2019)

The novel cyclophilin-D-interacting protein FASTKD1 protects cells against oxidative stress-induced cell death American Journal of Physiology - Cell Physiology (2019)

Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure JACC: Basic to Translational Science (2019)

Heterozygous deletion of AKT1 rescues cardiac contractility, but not hypertrophy, in a mouse model of Noonan Syndrome with Multiple Lentigines Journal of Molecular and Cellular Cardiology (2017)

Ischemia/reperfusion Comprehensive Physiology (2017)

Histone deacetyltransferase inhibitors Trichostatin A and Mocetinostat differentially regulate MMP9, IL-18 and RECK expression, and attenuate Angiotensin II-induced cardiac fibroblast migration and proliferation Hypertension Research (2016)

Metformin inhibits aldosterone-induced cardiac fibroblast activation, migration and proliferation in vitro, and reverses aldosterone + salt-induced cardiac fibrosis in vivo Journal of Molecular and Cellular Cardiology (2016)

Saxagliptin and tadalafil differentially alter cyclic guanosine monophosphate (cGMP) signaling and left ventricular function in aortic-banded mini-swine Journal of the American Heart Association (2016)

The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin-II-Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4 Journal of Cellular Physiology (2016)

Elevated Ca²⁺ transients and increased myofibrillar power generation cause cardiac hypercontractility in a model of Noonan syndrome with multiple lentigines American Journal of Physiology - Heart and Circulatory Physiology (2015)