Sumit Monu , PhD, DVM

Biography

I am trained in the field of physiology and pharmacology with extensive knowledge and experience in cardiovascular and renal research. My experience with kidney research began during my Ph.D. studies while working on to understand the role of Heme-oxygenase antioxidant system in the amelioration of myocardial infarction and cardio-renal syndrome. I joined the Hypertension and Vascular Research Division at Henry Ford Health System in Detroit for my postdoctoral studies. Continuing my interest in renal physiology I studied alterations in single nephron renal hemodynamics in animal models of obesity/prediabetes and unilateral nephrectomy. I also learnt the technique considered as the state of the art to measure tubuloglomerular feedback response at the single nephron level that took almost 1.5 years of intensive training. In-vivo renal micropuncture technique is the gold standard and the only technique to understand the single nephron renal hemodynamics in-vivo and only few labs in the whole world are able to perform this technique. Currently I am investigating the role of tubuloglomerular feedback mechanism, myogenic response and a relatively newly discovered feedback mechanism known as connecting tubule glomerular feedback in renal diseases especially that occurs in obesity and diabetes.