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Sing Lee

Sing Lee , PhD

he/his/him
Associate Professor
Pharmacology & Toxicology, Chemistry
B330 Life Sciences
Associations: Chemistry

Education

Ph.D., Chemistry, Michigan State University, 2003
Bachelor of Science, Chemistry, Hong Kong University of Science and Technology, 2000

Employment

Associate Professor, Michigan State University, East Lansing, 2024 - Present
Associate Professor, Michigan State University, East Lansing, 2024 - Present
Assistant Professor, Michigan State University, East Lansing, 2019 - Present
Assistant Professor, Michigan State University, East Lansing, 2017 - Present
Project Scientist, University of California Davis, Davis, 2014 - 2016
Post-doctoral Scholar, University of California Davis, Davis, 2010 - 2014

Publications

Effects of 17,18-Epoxyeicosatetraenoic Acid and 19,20-Epoxydocosapentaenoic Acid Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Brown Adipogenesis and Mitochondrial Respiration Nutrients (2025)

Effects of 17,18-Epoxyeicosatetraenoic Acid and 19,20-Epoxydocosapentaenoic Acid Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Brown Adipogenesis and Mitochondrial Respiration Nutrients (2025)

Quantitative Profiling Method for Oxylipins in Neurodegenerative Diseases by Liquid Chromatography Coupled with Tandem Mass Spectrometry (2023)

Cytochrome P450 and Epoxide Hydrolase Metabolites in Aβ and tau-induced Neurodegeneration: Insights fromCaenorhabditis elegans (2023)

Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues International Journal of Molecular Sciences (2021)

Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative Journal of Medicinal Chemistry (2021)

Cytochrome P450 Metabolism of Polyunsaturated Fatty Acids and Neurodegeneration Nutrients (2020)

Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain Bioorganic & Medicinal Chemistry (2020)

Inactivation of Cys 674 in SERCA2 increases BP by inducing endoplasmic reticulum stress and soluble epoxide hydrolase British Journal of Pharmacology (2020)

Asymmetric Total Synthesis of 19,20-Epoxydocosapentaenoic Acid, a Bioactive Metabolite of Docosahexaenoic Acid The Journal of Organic Chemistry (2019)