Jinda Fan

Assistant Professor
Toxicology & Pharmacology

fanjinda@msu.edu

517-432-2097

IQ Building Room 4117

Works

Protective Group-Dependent Iridium-Catalyzed CH Borylations of Levodopa. The Journal of Organic Chemistry (2025-05-27)
Species-Specific Hepatic Uptake of [⁶⁴Cu]Cu-EOB-NOTA, A Newly Designed Hepatospecific PET Agent. Molecular Imaging and Biology (2025)
The Development and Challenges of PET/MRI Dual-Modality Imaging Probes—An Update. Journal of Magnetic Resonance Imaging (2025)
Brown Adipose Tissue as a Unique Niche for Islet Organoid Transplantation: Insights From In Vivo Imaging. Transplantation Direct (2024)
Design and Construction of a Radiochemistry Laboratory and cGMP-Compliant Radiopharmacy Facility. Pharmaceuticals (2024)
Distribution of insulin in primate brain following nose-to-brain transport. Alzheimer's and Dementia: Translational Research and Clinical Interventions (2024)
On the inconsistencies in previously reported protections of the catechol moiety of L-DOPA. Tetrahedron Letters (2024)
Intra-Arterial Delivery of Radiopharmaceuticals in Oncology: Current Trends and the Future of Alpha-Particle Therapeutics. Pharmaceutics (2023-04-04)
Deep learning-enabled quantification of simultaneous PET/MRI for cell transplantation monitoring. iScience (2023)
Omniparticle Contrast Agent for Multimodal Imaging: Synthesis and Characterization in an Animal Model. Molecular Imaging and Biology (2023)
Pb-214/Bi-214-TCMC-Trastuzumab inhibited growth of ovarian cancer in preclinical mouse models. Frontiers in Chemistry (2023)
A concise review: the synergy between artificial intelligence and biomedical nanomaterials that empowers nanomedicine. Biomedical Materials (2021-09-01)
A concise review: The synergy between artificial intelligence and biomedical nanomaterials that empowers nanomedicine. Biomedical Materials (Bristol) (2021)
Dynamic neuroimaging of intranasal-administered radiotracers to assess brain waste clearance. Journal of Nuclear Medicine (2021)
Multifunctional thio-stabilized gold nanoparticles for near-infrared fluorescence detection and imaging of activated caspase-3. Current Analytical Chemistry (2021)
Multifunctional Thio-Stabilized Gold Nanoparticles for Near-Infrared Fluorescence Detection and Imaging of Activated Caspase-3. Current Analytical Chemistry (2021)
PET imaging for optimization of intranasal insulin in nonhuman primates. Journal of Nuclear Medicine (2021)
Therapeutic Efficacy of Pb-214-labeled Trastuzumab in a Preclinical Model of Ovarian Cancer. Journal of Nuclear Medicine (2021)
Current Progress and Perspective: Clinical Imaging of Islet Transplantation. Life (2020-09-19)
Current progress and perspective: Clinical imaging of islet transplantation. Life (2020)
Automated radiosynthesis of a PDE10A PET radiotracer: [¹⁸F]TZ20A-two-pot, two-step, and two-HPLC purification on one module. Journal of Labelled Compounds (2019)
Automated radiosynthesis of high specific activity [¹¹C]MeOTf and clinical-grade [¹¹C]PiB using a commercial Synthra synthesizer. Journal of Nuclear Medicine (2019)
212Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models. Nuclear Medicine and Biology (2018)
²¹²Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models. Nuclear Medicine and Biology (2018)
²¹²Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models. Nuclear Medicine and Biology (2018)
²¹²Pb-labeled antibody 225.28 targeted to chondroitin sulfate proteoglycan 4 for triple-negative breast cancer therapy in mouse models. International Journal of Molecular Sciences (2018)
²¹²Pb-Labeled Antibody 225.28 Targeted to Chondroitin Sulfate Proteoglycan 4 for Triple-Negative Breast Cancer Therapy in Mouse Models. International Journal of Molecular Sciences (2018)
Bioprocess development of antibody-drug conjugate production for cancer treatment. PLoS ONE (2018)
Corrigendum to ‘²¹²Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models’ [Nucl Med Biol 58 (2018) 67–73] (S0969805117303396) (10.1016/j.nucmedbio.2017.12.004)). Nuclear Medicine and Biology (2018)
²¹²Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models (vol 58, pg 67, 2018 ). Nuclear Medicine and Biology (2018)
Radiosynthesis and evaluation of fluorine-18 and carbon-11 radiotracers for PET Imaging of PDE10A in colorectal cancer. Abstracts of Papers of the American Chemical Society (2018)
B7-H3-targeted ²¹²Pb radioimmunotherapy of ovarian cancer in preclinical models. Nuclear Medicine and Biology (2017)
B7-H3-targeted ²¹²Pb radioimmunotherapy of ovarian cancer in preclinical models. Nuclear Medicine and Biology (2017)
Targeted radioimmunotherapy of triple negative breast cancer with CSPG4-specific 212Pb-labeled monoclonal antibody. Journal of Nuclear Medicine (2016)
Targeted radioimmunotherapy with B7-H3-specific 212Pb-mAb 376.96 in models of human ovarian cancer. Journal of Nuclear Medicine (2016)
IND-Directed Safety and Biodistribution Study of Intravenously Injected Cetuximab-IRDye800 in Cynomolgus Macaques. Molecular Imaging and Biology (2015)
Synthesis of fluorine-containing phosphodiesterase 10A (PDE10A) inhibitors and the in vivo evaluation of F-18 labeled PDE10A PET tracers in rodent and nonhuman primate. Journal of Medicinal Chemistry (2015)
Synthesis of Fluorine-Containing Phosphodiesterase 10A (PDE10A) Inhibitors and the In Vivo Evaluation of F-18 Labeled PDE10A PET Tracers in Rodent and Nonhuman Primate. Journal of Medicinal Chemistry (2015)
Automated radiochemical synthesis and biodistribution of [¹¹C]l-α-acetylmethadol ([¹¹C]LAAM). Applied Radiation and Isotopes (2014)
Automated radiochemical synthesis and biodistribution of [¹¹C]l-α-acetylmethadol ([¹¹C]LAAM). Applied Radiation and Isotopes (2014)
Dose escalation and dosimetry of first-in-human α radioimmunotherapy with ²¹²Pb-TCMC-trastuzumab. Journal of Nuclear Medicine (2014)
Dose Escalation and Dosimetry of First-in-Human α Radioimmunotherapy with ²¹²Pb-TCMC-Trastuzumab. Journal of Nuclear Medicine (2014)
Preclinical evaluation of a novel radiotracer [¹¹C]TZ-19-64B for imaging of PDE10A. Journal of Nuclear Medicine (2014)
Radiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primate. Bioorganic and Medicinal Chemistry (2014)
Radiosynthesis and in vivo evaluation of a novel σ₁ selective PET ligand. MedChemComm (2014)
Radiosynthesis and in vivo evaluation of a novel σ₁ selective PET ligand. MedChemComm (2014)
Radiosynthesis and in vivo evaluation of two PET radioligands for imaging α-synuclein. Applied Sciences (Switzerland) (2014)
Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein. Applied Sciences (2014)
Positron emission tomography imaging of dopamine D₂ receptors using a highly selective radiolabeled D₂ receptor partial agonist. NeuroImage (2013)
A novel fluorine-18 PET radiotracer for imaging sigma-1 receptor in the brain. Journal of Nuclear Medicine (2012)
Synthesis and validation of two potent F-18 labeled VAChT PET probes. Journal of Nuclear Medicine (2012)
Automated radiosynthesis of [¹¹C]morphine for clinical investigation. Applied Radiation and Isotopes (2011)
Automated radiosynthesis of [¹¹C]morphine for clinical investigation. Applied Radiation and Isotopes (2011)
Chemical and enzyme-assisted syntheses of norbuprenorphine-3-β-D- glucuronide. Bioconjugate Chemistry (2011)
Chemical and Enzyme-Assisted Syntheses of Norbuprenorphine-3-β-D-glucuronide. Bioconjugate Chemistry (2011)
Development of a Carbon-11 PET tracer for imaging the Dopamine D₃ receptor. Journal of Labelled Compounds and Radiopharmaceuticals (2011)
High in vivo occupancy of D3 and not D2 receptors: A PET study using D2-and D3-selective radiotracers. Journal of Nuclear Medicine (2011)
Radiosynthesis and in vivo evaluation of [ ¹¹C]MP-10 as a PET probe for imaging PDE10A in rodent and non-human primate brain. Bioorganic and Medicinal Chemistry (2011)
Radiosynthesis and in vivo evaluation of [¹¹C]MP-10 as a PET probe for imaging PDE10A in rodent and non-human primate brain. Bioorganic & Medicinal Chemistry (2011)
Radiosynthesis of a new fluorine-18 labeled carbamate compound as a potential σ₂ receptor PET radiotracer. Journal of Labelled Compounds and Radiopharmaceuticals (2011)
Single step aerosol synthesis of nanocomposites by aerosol routes: γ-Fe₂O₃/SiO₂ and their functionalization. Journal of Materials Research (2011)
Automated radio-synthesis of clinical-grade [¹¹C]morphine with a methylation module. Journal of Nuclear Medicine (2010)
Bright fluorescent nanoparticles for developing potential optical imaging contrast agents. Nanoscale (2010)
Differential distribution of dopamine D₂and D₃ receptors in the Rhesus brain measured with PET. Journal of Nuclear Medicine (2010)
Activatable molecular systems using homologous near-infrared fluorescent Probes for monitoring enzyme activities in vitro, in pCellulo, and in vivo. Molecular Pharmaceutics (2009)
Activatable Molecular Systems Using Homologous Near-Infrared Fluorescent Probes for Monitoring Enzyme Activities in Vitro, in Cellulo, and in Vivo. Molecular Pharmaceutics (2009)
Enhanced contrast dual modality imaging approach for screening of epithelial cancers. Optics InfoBase Conference Papers (2009)
INOR 438-Chemical and biochemical contrast strategies for optical imaging of molecular processes in vivo. Abstracts of Papers of the American Chemical Society (2008)
Nanoparticle-supported catalysts and catalytic reactions–a mini-review. Journal of Experimental Nanoscience (2006)
Nanoparticle-supported catalysts and catalytic reactions - a mini-review. Journal of Experimental Nanoscience (2006)
Recycling of homogeneous Pd catalysts using superparamagnetic nanoparticles as novel soluble supports for Suzuki, Heck, and Sonogashira cross-coupling reactions. Chemical Communications (2005)
Superparamagnetic nanoparticle-supported catalysis of Suzuki cross-coupling reactions. Organic Letters (2005)
Cross-linking the linear polymeric chains in the ATRP synthesis of iron oxide/polystyrene core/shell nanoparticles. Chemistry of Materials (2004)
Coating gold nanoparticles with peptide molecules via a peptide elongation approach. Colloids and Surfaces B: Biointerfaces (2003)
Synthesis of alkyl sulfonate/alcohol-protected γ-Fe₂O₃ nanocrystals with narrow size distributions. Journal of Colloid and Interface Science (2003)
Use of water-dispersible Fe₂O₃ nanoparticles with narrow size distributions in isolating avidin. Journal of Colloid and Interface Science (2003)
Encapsulation of uranyl acetate molecules using hollow polymer templates. Journal of Colloid and Interface Science (2002)

Employment

Assistant Professor, Michigan State University (2019-07-01)
Assistant Professor, University of Alabama at Birmingham (2012-07-01—2019-06-30)
Postdoc/Staff Scientist, Washington University in St. Louis (2006-05-16—2012-06-30)
Graduate Student, Southern Illinois University Carbondale (2000-08-10—2006-05-15)