David Escobar , PhD
2799 W GRAND BLVD
Education
PhD in Cellular and Molecular Biology, Department of Molecular and Cellular Biology, University of Concepcion, 2009
Biochemist, , University of Concepcion, 2003
Employment
Research Scientist/Instructor, Pancreatic Cancer Center Henry Ford Heatlh System, Detroit, 2025 - Present
Postdoctoral Research Associate , University of Toledo, Toledo, 2019 - 2025
Postdoctoral Felow, Northwestern University - Chicago, Chicago, 2016 - 2017
Publications
Single-cell RNA sequencing reveals the MIF/ACKR3 receptor-ligand interaction between neutrophils and nucleus pulposus cells in intervertebral disc degeneration. Translational research : the journal of laboratory and clinical medicine (2024)
Integrating single-cell and spatial transcriptomics reveals endoplasmic reticulum stress-related CAF subpopulations associated with chordoma progression. Neuro-oncology (2024)
A breast cancer classification and immune landscape analysis based on cancer stem-cell-related risk panel. NPJ precision oncology (2023)
Cardiovascular-specific mortality and risk factors in colorectal Cancer patients: A cohort study based on registry data of over 500,000 individuals in the US. Preventive medicine (2023)
A novel immune checkpoint-related signature for prognosis and immune analysis in breast cancer. Clinical and experimental medicine (2023)
A four-factor immune risk score signature predicts the clinical outcome of patients with spinal chordoma. Clinical and translational medicine (2020)
A Trichostatin A (TSA)/Sp1-mediated mechanism for the regulation of SALL2 tumor suppressor in Jurkat T cells. Biochimica et biophysica acta. Gene regulatory mechanisms (2018)
SALL2 represses cyclins D1 and E1 expression and restrains G1/S cell cycle transition and cancer-related phenotypes. Molecular oncology (2018)
ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer. Scientific reports (2017)
Developmental SALL2 transcription factor: a new player in cancer. Carcinogenesis (2017)