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David Escobar , PhD

Research Associate, Henry Ford Health System
Location: HENRY FORD HOSPITAL - DETROIT
2799 W GRAND BLVD
Department: Pharmacology & Toxicology

Education

PhD in Cellular and Molecular Biology, Department of Molecular and Cellular Biology, University of Concepcion, 2009
Biochemist, , University of Concepcion, 2003

Employment

Research Scientist/Instructor, Pancreatic Cancer Center Henry Ford Heatlh System, Detroit, 2025 - Present
Postdoctoral Research Associate , University of Toledo, Toledo, 2019 - 2025
Postdoctoral Felow, Northwestern University - Chicago, Chicago, 2016 - 2017

Publications

Single-cell RNA sequencing reveals the MIF/ACKR3 receptor-ligand interaction between neutrophils and nucleus pulposus cells in intervertebral disc degeneration. Translational research : the journal of laboratory and clinical medicine (2024)

Integrating single-cell and spatial transcriptomics reveals endoplasmic reticulum stress-related CAF subpopulations associated with chordoma progression. Neuro-oncology (2024)

A breast cancer classification and immune landscape analysis based on cancer stem-cell-related risk panel. NPJ precision oncology (2023)

Cardiovascular-specific mortality and risk factors in colorectal Cancer patients: A cohort study based on registry data of over 500,000 individuals in the US. Preventive medicine (2023)

A novel immune checkpoint-related signature for prognosis and immune analysis in breast cancer. Clinical and experimental medicine (2023)

A four-factor immune risk score signature predicts the clinical outcome of patients with spinal chordoma. Clinical and translational medicine (2020)

A Trichostatin A (TSA)/Sp1-mediated mechanism for the regulation of SALL2 tumor suppressor in Jurkat T cells. Biochimica et biophysica acta. Gene regulatory mechanisms (2018)

SALL2 represses cyclins D1 and E1 expression and restrains G1/S cell cycle transition and cancer-related phenotypes. Molecular oncology (2018)

ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer. Scientific reports (2017)

Developmental SALL2 transcription factor: a new player in cancer. Carcinogenesis (2017)