Making a
difference.
It's in our DNA.

Mary Underwood, PhD

Assistant Professor
Pharmacology & Toxicology
LSB B429

Education

  • Biomedical Sciences (BSc), , Imperial College London (2006—2009)

Funding

Works

  • Neonatal Encephalopathy: Novel Phenotypes and Genotypes Identified by Genome Sequencing. Neurology. Genetics (2025-01-13)
  • Genome-wide association and linkage analysis of histidine-rich glycoprotein identifies common variants associated with plasma histidine-rich glycoprotein concentrations. RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS (2025)
  • Identification of multiple novel procoagulant plasma ligands for stabilin-2. JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2025)
  • ADAMTS-13 conformation in fluences autoimmune recognition in immune thrombotic thrombocytopenic purpura. JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2024)
  • Venous thromboembolic disease genetics: from variants to function. JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2024)
  • Autoantibodies enhance ADAMTS-13 clearance in patients with immune thrombotic thrombocytopenic purpura. Journal of thrombosis and haemostasis : JTH (2023-02-20)
  • Whole-exome sequencing identifies rare variants in STAB2 associated with venous thromboembolic disease. Blood (2020-07-01)
  • Degradation of two novel congenital TTP ADAMTS13 mutants by the cell proteasome prevents ADAMTS13 secretion. Thrombosis research (2016-09-15)
  • ADAMTS13 Secretion and Residual Activity among Patients with Congenital Thrombotic Thrombocytopenic Purpura with and without Renal Impairment. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2015)
  • Congenital Thrombotic Thrombocytopenic Purpura With Novel Mutations in Three Unrelated Turkish Children. PEDIATRIC BLOOD & CANCER (2014)
  • Thrombotic thrombocytopenic purpura and pregnancy: presentation, management, and subsequent pregnancy outcomes. BLOOD (2014)
  • In vitro characterisation of two ADAMTS13 mutants (I143T, Y570C) identified in two patients with congenital thrombotic thrombocytopenic purpura (TTP). JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2013)
  • Mutations and polymorphisms in adult onset pregnancy related TTP. JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2013)
  • NINE NOVEL ADAMTS13 MUTATIONS IN CONGENITAL PREGNANCY ASSOCIATED ADULT ONSET TTP. HAEMATOLOGICA (2012)

Employment

  • Assistant Professor, Michigan State University (2025-09-01)
  • Postdoctoral Research Fellow, University of Michigan (2019—2025-07-04)
  • Postdoctoral Research Associate, Imperial College London (2015—2019)
  • Postdoctoral Research Technician, University College London (2014—2015)
  • PhD student, University College London (2010—2014)
  • Research Technician, University College London (2009—2010)