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James Luyendyk

James Luyendyk , PhD

Associate Dean for Research and Graduate Studies, College of Veterinary Medicine
Pathobiology & DIagnostic Investigation, Pharmacology & Toxicology
240H Food Safety and Toxicology Building
Associations: Institute for Integrative Toxicology

Employment

, Michigan State University, East Lansing, - Present

Publications

Age-associated increases in PAI-1 silenced with siRNA-lipid nanoparticles reduces thrombosis and prolongs lifespan Blood (2026)

Fibrin and Fibrinolysis in Liver, Kidney, and Lung Transplantation Arterioscler Thromb Vasc Biol (2026)

Role of the Plasminogen Activation System in Liver Injury and Repair: Knowns and Known Unknowns Arterioscler Thromb Vasc Biol (2026)

Tissue transglutaminase drives fibrin β-chain cross-linking: a novel fibrin modification observed in patients with trauma Blood (2026)

Urokinase Plasminogen Activator Deficiency Delays the Development of Obesity and Metabolic Sequelae Arterioscler Thromb Vasc Biol (2026)

Factor XIII: driving (cross-)links in hemostasis, thrombosis, and disease Blood (2025)

Integrated cross-linking by TG2 and FXIII generates hepatoprotective fibrin(ogen) deposits in injured liver Blood (2025)

Kupffer cell expression of macrophage receptor with collagenous structure modulates macrophage gene induction and limits acute liver injury Toxicol Sci (2025)

Platelets mediate neutrophil infiltration and exacerbate liver injury and sinusoidal endothelial cell damage after a severe acetaminophen overdose in mice Arch Toxicol (2025)

A bovine model of hypoxia-induced pulmonary hypertension reveals a gradient of immune and matrisome response with a complement signature found in circulation Am J Physiol Cell Physiol (2024)

In the News

Nana Kwame Kwabi Boateng, Dr. James Luyendyk Have Formed an "Amazing Connection"

The Ghana native sent a cold email from a colder Scotland to Dr. James Luyendyk seeking to study PhmTox at MSU and it has proven to be an educational relationship for both of them

Dr. James Luyendyk Selected Society of Toxicology Vice President-elect for 2024-25; Continues MSU's Legacy

Dr. James Luyendyk selected as SOT Vice President-elect and is the 10th MSU scientist to earn the distinction

Three PhmTox Faculty Honored with Chair Investitures

Drs. James Luyendyk, Anne Dorrance and Norbert Kaminski were among 49 honored at MSU's 2024 Investiture for Endowed Faculty

Four Pharmacology and Toxicology Professors Awarded Tetrad Research Funding

Drs. Lauver, Luyendyk, Dorrance and Fink have been awarded funding from the inaugural Tetrad Interdisciplinary fund program through the Office of Research and Innovation.