Jamie Bernard, PhD

she/her/hers
Associate Professor and Ph.D. Program Director
Pharmacology & Toxicology

jbernard@msu.edu

353-5326

B420 Life Sciences

Research

Mentees

Colleges

College of Human Medicine

Associations

Division of Dermatology

Programs

Sections

PHM 828 Concepts in Carcinogenesis (online) - Fall
PHM 910 Seminar (in-person) - Fall
PHM 899 Master's Thesis Research (in-person) - Fall
PHM 802 Cellular, Molecular and Integrated Systems Pharmacology (in-person) - Spring
PHM 899 Master's Thesis Research (in-person) - Spring
PHM 910 Seminar (in-person) - Spring
PHM 899 Master's Thesis Research (in-person) - Summer

Works

Adipocyte-derived kynurenine stimulates malignant transformation of mammary epithelial cells through the aryl hydrocarbon receptor. Biochemical Pharmacology (2023)
The Tumor Promotional Role of Adipocytes in the Breast Cancer Microenvironment and Macroenvironment. The American Journal of Pathology (2021)
Photoimmunology: how ultraviolet radiation affects the immune system. Nature Reviews Immunology (2019-11-18)
Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay. Scientific reports (2019-07-16)
Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay. Scientific Reports (2019-07-16)
Lipectomizing Mice for Applications in Metabolism. Methods in molecular biology (Clifton, N.J.) (2019-01-01)
Lipectomizing mice for applications in metabolism. Methods in Molecular Biology (2019)
A role for FGF2 in visceral adiposity-associated mammary epithelial transformation. Adipocyte (2018-03-21)
A role for FGF2 in visceral adiposity-associated mammary epithelial transformation. Adipocyte (2018)
Why does a high-fat diet increase cancer risk?. Future oncology (London, England) (2018-02-07)
A BET Bromodomain Inhibitor Suppresses Adiposity-Associated Malignant Transformation. Cancer prevention research (Philadelphia, Pa.) (2017-12-15)
A BET bromodomain inhibitor suppresses adiposity-associated malignant transformation. Cancer Prevention Research (2018)
Elucidating the role of adipose tissue secreted factors in malignant transformation. Adipocyte (2017-11-02)
Elucidating the role of adipose tissue secreted factors in malignant transformation. Adipocyte (2018)
Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer. Oncogene (2017-08-07)
Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer. Oncogene (2017)
Deciphering metabolic rewiring in breast cancer subtypes. Translational research : the journal of laboratory and clinical medicine (2017-07-15)
Deciphering metabolic rewiring in breast cancer subtypes. Translational Research (2017)
PDE2 is a novel target for attenuating tumor formation in a mouse model of UVB-induced skin carcinogenesis. PloS one (2014-10-16)
PDE2 is a novel target for attenuating tumor formation in a mouse model of UVB-induced skin carcinogenesis. PLoS ONE (2014)
Toll-like receptor 3 activation is required for normal skin barrier repair following UV damage. The Journal of investigative dermatology (2014-08-12)
Toll-like receptor 3 activation is required for normal skin barrier repair following UV damage. Journal of Investigative Dermatology (2015)
Parametrial fat tissue from high fat diet-treated SKH-1 mice stimulates transformation of mouse epidermal JB6 cells. Journal of carcinogenesis & mutagenesis (2014-07-01)
Innate immune sensors stimulate inflammatory and immunosuppressive responses to UVB radiation. The Journal of investigative dermatology (2014-06-01)
Innate immune sensors stimulate inflammatory and immunosuppressive responses to UVB radiation. Journal of Investigative Dermatology (2014)
Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice. Experimental and molecular pathology (2013-10-30)
Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice. Experimental and Molecular Pathology (2014)
Oral caffeine during voluntary exercise markedly inhibits skin carcinogenesis and decreases inflammatory cytokines in UVB-treated mice. Nutrition and cancer (2013-09-26)
Oral caffeine during voluntary exercise markedly inhibits skin carcinogenesis and decreases inflammatory cytokines in UVB-treated mice. Nutrition and Cancer (2013)
Inhibition of UVB-induced nonmelanoma skin cancer: a path from tea to caffeine to exercise to decreased tissue fat. Topics in current chemistry (2013-01-01)
Inhibition of UVB-induced nonmelanoma skin cancer: A path from tea to caffeine to exercise to decreased tissue fat. Topics in Current Chemistry (2013)
Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nature medicine (2012-07-08)
Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nature Medicine (2012)
Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet. Proceedings of the National Academy of Sciences of the United States of America (2012-05-21)
Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet. Proceedings of the National Academy of Sciences of the United States of America (2012)
Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptides. Journal of immunology (Baltimore, Md. : 1950) (2011-12-02)
Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptides. Journal of Immunology (2012)
Protecting the boundary: the sentinel role of host defense peptides in the skin. Cellular and molecular life sciences : CMLS (2011-05-15)
Protecting the boundary: The sentinel role of host defense peptides in the skin. Cellular and Molecular Life Sciences (2011)
The Feverfew plant-derived compound, parthenolide enhances platelet production and attenuates platelet activation through NF-κB inhibition. Thrombosis research (2011-01-26)
The Feverfew plant-derived compound, parthenolide enhances platelet production and attenuates platelet activation through NF-κB inhibition. Thrombosis Research (2011)
Cyclooxygenase-2 enhances antimicrobial peptide expression and killing of Staphylococcus aureus. Journal of immunology (Baltimore, Md. : 1950) (2010-10-22)
Cyclooxygenase-2 enhances antimicrobial peptide expression and killing of staphylococcus aureus. Journal of Immunology (2010)
Foxp3 regulates megakaryopoiesis and platelet function. Arteriosclerosis, thrombosis, and vascular biology (2009-08-06)
Foxp3 regulates megakaryopoiesis and platelet function. Arteriosclerosis, Thrombosis, and Vascular Biology (2009)
15-deoxy-Delta12,14 prostaglandin J2-induced heme oxygenase-1 in megakaryocytes regulates thrombopoiesis. Journal of thrombosis and haemostasis : JTH (2008-10-10)
15-deoxy-Δ^12,14 prostaglandin J2-induced heme oxygenase-1 in megakaryocytes regulates thrombopoiesis. Journal of Thrombosis and Haemostasis (2009)
15-deoxy-delta12,14-PGJ2 enhances platelet production from megakaryocytes. Blood (2008-08-28)
15-deoxy-{Delta}12,14-PGJ2 enhances platelet production from megakaryocytes. Blood (2008)
Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles. Thrombosis and haemostasis (2008-01-01)
Peroxisome proliferator-activated receptor γ and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles. Thrombosis and Haemostasis (2008)
The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects. PPAR research (2008-01-01)
The platelet as a therapeutic target for treating vascular diseases and the role of eicosanoid and synthetic PPARgamma ligands. Prostaglandins & other lipid mediators (2006-07-10)
The platelet as a therapeutic target for treating vascular diseases and the role of eicosanoid and synthetic PPARγ ligands. Prostaglandins and Other Lipid Mediators (2007)
Platelets as a novel target for PPARgamma ligands : implications for inflammation, diabetes, and cardiovascular disease. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy (2006-01-01)
Platelets as a novel target for PPARγ ligands: Implications for inflammation, diabetes, and cardiovascular disease. BioDrugs (2006)