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Chris Occhiuto

Chris Occhiuto

Graduate Student
Year Start: 2021
Degree: MD PhD, Pharmacology & Toxicology
External Mentor: Karen Liby

Education

PhD, Pharmacology and Toxicology, Michigan State University, 2019
MD, College of Human Medicine, Michigan State University, 2019
BS, Physiology, Michigan State University, 2015

Employment

MD/PhD Trainee, Michigan State University, East Lansing, 2019 - Present

Publications

Synthetic Oleanane Triterpenoids Reduce Tumor Growth and Promote an Anti-Tumor Immune Response Independent of Cancer KEAP1 Mutational Status Antioxidants (2025)

Synthetic Oleanane Triterpenoids Reduce Tumor Growth and Promote an Anti-Tumor Immune Response Independent of Cancer KEAP1 Mutational Status Antioxidants (2025)

KEAP1-Mutant Lung Cancers Weaken Anti-Tumor Immunity and Promote an M2-like Macrophage Phenotype International Journal of Molecular Sciences (2024)

KEAP1-Mutant Lung Cancers Weaken Anti-Tumor Immunity and Promote an M2-like Macrophage Phenotype International Journal of Molecular Sciences (2024)

The Multi-Faceted Consequences of NRF2 Activation throughout Carcinogenesis Molecules and Cells (2023)

Exploring structural effects in a new class of NRF2 inhibitors RSC Medicinal Chemistry (2023)

A Critical Role for Na+/H+ Exchanger Regulatory Factor 1 in Modulating FcεRI-Mediated Mast Cell Activation The Journal of Immunology (2021)

A critical role for Na+/H+ exchanger regulatory factor 1 in modulating Fc«RI-mediated mast cell activation Journal of Immunology (2021)

Osthole, a Natural Plant Derivative Inhibits MRGPRX2 Induced Mast Cell Responses Frontiers in Immunology (2020)

Store-Operated Calcium Entry via STIM1 Contributes to MRGPRX2 Induced Mast Cell Functions Frontiers in Immunology (2020)

Canonical and Noncanonical Signaling Roles of β-Arrestins in Inflammation and Immunity Advances in Immunology (2017)

Roles of NHERF Family of PDZ-Binding Proteins in Regulating GPCR Functions Advances in Immunology (2017)