Adam Lauver, PhD
he/his/him
Associate Professor
Pharmacology & Toxicology
Associate Professor
Pharmacology & Toxicology
Lab Staff
Mentees
Colleges
Programs
Education
- Postdoctoral, Pharmacology, University of Michigan (2007—2011)
- Ph.D., Pharmacology, University of Michigan (2002—2007)
- B.S., , Pennsylvania State University (1997—2001)
Funding
- Perivascular Adipose Tissue (PVAT) as a Central Integrator of Vascular Health, National Heart Lung and Blood Institute (2021-12-22—2026-11-30)
Works
- The “One‐Step” approach for QT analysis increases the sensitivity of nonclinical QTc analysis. Clinical and Translational Science (2023)
- Improving corrected QT; Why individual correction is not enough. Journal of Pharmacological and Toxicological Methods (2022)
- Pleiotropic effects of clopidogrel. Purinergic Signalling (2022)
- QT Ratio: A simple solution to individual QT correction. Journal of Pharmacological and Toxicological Methods (2022)
- Clopidogrel treatment inhibits P2Y2-Mediated constriction in the rabbit middle cerebral artery. European Journal of Pharmacology (2021)
- Clopidogrel treatment inhibits P2Y2-Mediated constriction in the rabbit middle cerebral artery. European Journal of Pharmacology (2021)
- DT‐678 inhibits platelet activation with lower tendency for bleeding compared to existing P2Y12 antagonists. Pharmacology Research & Perspectives (2019)
- DT-678 inhibits platelet activation with lower tendency for bleeding compared to existing P2Y12 antagonists. Pharmacology Research and Perspectives (2019)
- Relationship of clinical adverse event reports to models of arrhythmia risk. Journal of Pharmacological and Toxicological Methods (2019)
- Significant Improvement of Antithrombotic Responses to Clopidogrel by Use of a Novel Conjugate as Revealed in an Arterial Model of Thrombosis. The Journal of pharmacology and experimental therapeutics (2016)
- Significant improvement of antithrombotic responses to clopidogrel by use of a novel conjugate as revealed in an arterial model of thrombosiss. Journal of Pharmacology and Experimental Therapeutics (2016)
- Sildenafil citrate for prophylaxis of nephropathy in an animal model of contrast-induced acute kidney injury. PloS one (2014)
- Sildenafil citrate for prophylaxis of nephropathy in an animal model of contrast-induced acute kidney injury. PLoS ONE (2014)
- CYP-independent inhibition of platelet aggregation in rabbits by a mixed disulfide conjugate of clopidogrel. Thrombosis and haemostasis (2014)
- CYP-independent inhibition of platelet aggregation in rabbits by a mixed disulfide conjugate of Clopidogrel. Thrombosis and Haemostasis (2014)
- Oral pretreatment with liposomal glutathione attenuates reperfusion injury in rabbit isolated hearts. Journal of cardiovascular pharmacology (2013)
- Oral pretreatment with liposomal glutathione attenuates reperfusion injury in rabbit isolated hearts. Journal of Cardiovascular Pharmacology (2013)
- Formation, reactivity, and antiplatelet activity of mixed disulfide conjugates of clopidogrel. Molecular pharmacology (2013)
- Formation, reactivity, and antiplatelet activity of mixed disulfide conjugates of clopidogrel. Molecular Pharmacology (2013)
- Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1. Proceedings of the National Academy of Sciences of the United States of America (2010)
- Disodium disuccinate astaxanthin prevents carotid artery rethrombosis and ex vivo platelet activation. Pharmacology (2008)
- Sulodexide: A renewed interest in this glycosaminoglycan. Cardiovascular Drug Reviews (2006)
- Disodium disuccinate astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion. Journal of Pharmacology and Experimental Therapeutics (2005)
- Sulodexide attenuates myocardial ischemia/reperfusion injury and the deposition of C-reactive protein in areas of infarction without affecting hemostasis. Journal of Pharmacology and Experimental Therapeutics (2005)
- Comparative analysis of various platelet glycoprotein IIb/IIIa antagonists on shear-induced platelet activation and adhesion. Journal of Pharmacology and Experimental Therapeutics (2002)
Employment
- Assistant Professor, Michigan State University (2016-11-01)
- Research Investigator, University of Michigan (2011—2016-10-31)
- , Bristol-Myers Squibb Co (2001—2002)